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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
31.52
Human Site:
S2118
Identified Species:
57.78
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
S2118
E
L
L
H
S
K
H
S
H
P
L
D
S
N
Q
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S2132
E
L
L
H
S
K
H
S
H
P
L
D
S
N
Q
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
S2118
E
L
L
H
S
K
H
S
H
P
L
D
S
N
Q
Dog
Lupus familis
XP_537704
2182
240593
S2126
E
L
L
H
S
K
H
S
H
P
L
D
S
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
S2115
E
L
L
H
S
K
H
S
H
P
L
D
S
N
Q
Rat
Rattus norvegicus
NP_001100505
2040
223488
H1985
L
L
H
S
K
H
S
H
P
L
D
S
N
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
S2114
E
L
L
H
S
K
H
S
H
P
L
D
S
N
Q
Chicken
Gallus gallus
XP_415884
2225
244861
S2169
E
L
L
H
S
K
H
S
H
P
L
D
S
N
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
S2046
E
L
L
H
S
K
H
S
H
P
L
D
S
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
N2555
D
D
I
L
N
S
T
N
A
H
Q
S
G
N
D
Honey Bee
Apis mellifera
XP_393643
1982
216109
H1927
Q
Q
S
A
L
T
A
H
P
L
D
S
Q
Y
T
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
A2805
K
E
K
D
E
K
D
A
H
P
L
E
S
R
Q
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
H1072
I
L
Q
T
K
H
S
H
P
L
D
S
D
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
100
N.A.
86.6
N.A.
6.6
0
40
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
100
N.A.
93.3
N.A.
33.3
6.6
60
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
8
0
0
8
0
0
0
24
62
8
0
8
% D
% Glu:
62
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
8
62
0
16
62
24
70
8
0
0
0
0
8
% H
% Ile:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
0
16
70
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
77
62
8
8
0
0
0
0
24
70
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
8
62
0
% N
% Pro:
0
0
0
0
0
0
0
0
24
70
0
0
0
0
0
% P
% Gln:
8
8
8
0
0
0
0
0
0
0
8
0
8
8
62
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% R
% Ser:
0
0
8
8
62
8
16
62
0
0
0
31
70
8
0
% S
% Thr:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
24
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _